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Mark Twain Brewing Co.


Mon-Thu: 11am-10pm
Fri-Sat: 11am-1:30am
Sun: 11am-9pm


About Mark Twain Brewing Co.

Located across the street from the home of the legendary Mark Twain in an old Model T manufacturing facility, Mark Twain Brewing is historical to its core. Each of their five year-round brews and seasonals are named after one of Twain’s tales: Huck Finn’s Habanero Apricot Wheat, Halley’s Blueberry Saison, King Arthur’s Court Imperial IPA and Clemens’ Kölsch just to name a few. As a bonus, the space boasts killer views from their second floor balcony, which overlooks the Mississippi River.

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Mark Twain Brewing Co.

422 N Main St
Hannibal, MO 63401


Schlafly buys Trailhead Brewing in St. Charles

Schlafly buys Trailhead Brewing in St. Charles

A St. Charles institution for 25 years, Trailhead Brewing Co. has been sold to Schlafly Beer.

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There's Always Something Brewing

The Greater St. Louis Metro Area currently has over 60 breweries and even more to come. When planning a visit, please note that not every brewery offers tours or has a tasting room/restaurant, and hours of operation vary. For the most up-to-date information, visit individual brewery websites or call ahead.